Treatment for Epstein-Barr Virus-associated uveitis confirmed by polymerase chain reaction: Efficacy of Anti-Viral Agents and a literature review

1st Author: Sukhum Silpa-Archa et al. (2022)

Key point:
Our study and review of the literature concurred that there was an absence of EBV DNA in the eyes of healthy controls, while pathogenicity of EBV in uveitis patients was confirmed.

In uveitis patients, EBV can be solely present or can co-exist with other pathogens.

The efficacy levels of systemic acyclovir for the treatment of EBV-associated uveitis patients were confirmatory, while systemic acyclovir and ganciclovir had comparable EBV viral suppression effects.

A stepwise algorithm has been proposed to help ophthalmologists in the management of EBV-associated intraocular inflammation.