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Sexually Transmitted Infections
Detect and identify 14 different causative pathogens
1,579,885

Chlamydia is the most frequently reported bacterial STI in the United States.

In 2020, a total of 1,579,885 cases of Chlamydia trachomatis infection were reported to the CDC, making it the most common notifiable sexually transmitted infection in the United States for that year.

Product Information
Analytes

Analytes
Chlamydia trachomatis (CT)
Neisseria gonorrhoeae (NG)
Mycoplasma genitalium (MG)
Mycoplasma hominis (MH)
Trichomonas vaginalis (TV)
Ureaplasma urealyticum (UU)
Ureaplasma parvum (UP)

Analytes
Herpes simplex virus type 1 (HSV-1)
Herpes simplex virus type 2 (HSV-2)
Cytomegalovirus (CMV)
Varicella-zoster virus (VZV)
C . trachomatis serovar L (LGV)
Treponema pallidum (TP)
Haemophilus ducreyi (HD)

Analytes
Chlamydia trachomatis (CT)
Mycoplasma genitalium (MG)
Neisseria gonorrhoeae (NG)
Trichomonas vaginalis (TV)

Analytes
Monkeypox virus (MPXV)

Specimen

Genital swab
Oropharyngeal (throat) swab
Anorectal swab
Liquid-based cytology
Urine
Semen

Genital swab
Liquid based cytology
Urine

Genital swab
Oropharyngeal (throat) swab
Anorectal swab
Liquid-based cytology
Urine
Semen

Compatible instrumentation

Automated Extraction & PCR Setup
Seegene NIMBUS
Seegene STARlet

Real-time PCR
CFX96™ Real-time PCR System (Bio-Rad)
CFX96™ Dx Systems (Bio-Rad)
CFX96™ Opus (Bio-Rad)
CFX96 Touch™ Real-Time PCR Detection System (Bio-Rad)

Seegene Viewer Software

  • Quick and easy data analysis and interpretation
  • Interface specialized for multiplex testing
Key Features
  • Simultaneous detection of multiple STI pathogens 
  • Short TAT (4 hours) from extraction to final results
  • Informative data with individual Ct value for each analyte
Ordering Information

Select the assays you are interested in and a Seegene representative will contact you to complete your order.

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Understanding Sexually Transmitted Infections

Sexually transmitted infections (STIs) are among the most common infectious conditions and are a substantial cause of morbidity and mortality worldwide, with 1 million new curable cases every day. STIs severely impact sexual and reproductive health and can also be transmitted to sexual partners and newborns. STIs cause sexually transmitted diseases (STDs), such as chlamydia Chlamydia trachomatis (CT), gonorrhea (Neisseria gonorrhea (NG), and Trichomoniasis vaginalis (TV).

CT infection, the most common bacterial STI, causes several urogenital syndromes, including urethritis, epididymitis, prostatitis, and cervicitis.1 In some women, CT infections may ascend to the upper genital tract and become chronic, leading to long-term sequelae, such as reproductive complications including pelvic inflammatory disease (PID), ectopic pregnancy, tubal infertility, or inducing adverse pregnancy outcomes.2,3 CT infections are also associated with an increased risk of cervical cancer, HIV acquisition, and transmission.4 

Gonorrhea is the second most reported bacterial sexually transmitted infection in the United States. Urethral infections caused by NG can produce symptoms among men, but often not soon enough to prevent transmission to others.5 Among women, gonococcal infections are commonly asymptomatic or might not produce recognizable symptoms until complications have occurred.6

Seegene provides an extensive multiplex sexually transmitted infection (STI) test menu for use in research testing.

The Novaplex™ STI Essential Assay*, Novaplex™ Genital Ulcer Assay* and Novaplex™ CT/NG/MG/TV Assay* are multiplex, real-time RT-PCR assays that detect and identify 14 STI pathogens simultaneously.

Novaplex™ MPOX Assay* is a real-time PCR product that is designed to specifically detect the R1R gene, providing specific detection of the monkeypox virus with a single test while limiting reactivity with other orthopox viruses or the Jynneos vaccine. This product can be used with Seegene’s automation solution or others for a convenient workflow.

*Novaplex™ Assays are For Research Use Only. Not for Use in Diagnostic Procedures.

Studies

Elbaz M, Halutz O, Ali Y, Adler A. Diagnosis of Monkeypox infection: Validation of two diagnostic kits for viral detection using RT-PCR. J Virol Methods. 2023 Feb;312:114653. doi: 10.1016/j.jviromet.2022.114653. Epub 2022 Nov 14. PMID: 36395919; PMCID: PMC9661602. 

A Multi-Laboratory Evaluation of Commercial Monkeypox Molecular Tests. Oran Erster, Itzchak Levy, Areej Kabat, Batya Menasheh, Virginia Levy, Hadar Assraf, Roberto Azar, Haim Ben-Zvi, Rita Bridenstein, Olga Bondar, Ayman Fadeela, Ayelet Keren-Naus, Avi Peretz, Diana Roif-Kaminsky, Lolu Saleh, Lisita Schreiber, Orna Schwartz, Pninit Shaked, Nadav Sorek, Merav Strauss, Rachel Steinberg, Orit Treygerman, Simona Zisman-Rozen, Ruth Yshai, Noa Tejman-Yarden, Ella Mendelson, Danit Sofer. medRxiv 2022.11.27.22282791; doi: 

1 K Manavi. A review on infection with Chlamydia trachomatis. Best Pract Res Clin Obstet Gynaecol. 2006 Dec;20(6):941-51. doi: 10.1016/j.bpobgyn.2006.06.003. Epub 2006 Aug 24.
2 CL Haggerty et al., Risk of sequelae after Chlamydia trachomatis genital infection in women. J Infect Dis. 2010 Jun 15;201 Suppl 2:S134-55. doi: 10.1086/652395.
3 A Ammerdorffer et al., Chlamydia trachomatis and chlamydia-like bacteria: new enemies of human pregnancies. Curr Opin Infect Dis. 2017 Jun;30(3):289-296. doi: 10.1097/QCO.0000000000000369.
4 K Adachi et al., Chlamydia and Gonorrhea in HIV-Infected Pregnant Women and Infant HIV Transmission. Sex Transm Dis. 2015 Oct;42(10):554-65. doi: 10.1097/OLQ.0000000000000340.
5 LM Valley et al., Adverse pregnancy and neonatal outcomes associated with Neisseria gonorrhoeae: systematic review and meta-analysis. Sex Transm Infect. 2021 Mar;97(2):104-111. doi: 10.1136/sextrans-2020-054653. Epub 2021 Jan 12.
6 KA Workowski et al., Sexually Transmitted Infections Treatment Guidelines, MMWR Recomm Rep 2021;70(4):1-187. doi: 10.15585/mmwr.rr7004a1.
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