Every year more than 1.2 million people worldwide suffer from meningitis1
Approximately 10% of patients die2
20% of survivors suffer from permanent debilitation (e.g., hearing loss, brain damage, loss of limbs, other serious effects)2
Nearly 50% of cases of bacterial meningitis occurs in children under five years of age1
Meningitis is an inflammation of the protective membranes covering the brain and spinal cord, typically caused by a bacterial or viral infection of the cerebrospinal fluid (CSF). Injuries, cancer, certain drugs, and other types of infections also can cause meningitis.
The cerebrospinal fluid (CSF) culture and Gram stain are typically used to detect meningitis. However, sensitivity of these methods is limited, particularly when patients receive antimicrobial treatment prior to CSF collection. The use of real-time PCR can improve the detection of meningitis pathogens; multiplex real-time PCR allows simultaneous detection of multiple pathogens in a single reaction.
Novaplex™ Meningitis Panel Assays* are a multiplex real-time RT-PCR assay that detects and identifies 18 meningitis pathogens, including 6 bacteria and 12 viruses, simultaneously. Based on Seegene’s proprietary MuDT™ technology, this assay makes it possible to report multiple Ct values in a single channel without melting curve analysis.
*Novaplex™ Assays are For Research Use Only. Not for Use in Diagnostic Procedures.
Virus (I)
Herpes simplex virus type 1 (HSV1)
Varicella-zoster virus (VZV)
Cytomegalovirus (CMV)
Human herpesvirus 7 (HHV7)
Herpes simplex virus type 2 (HSV2)
Epstein-barr virus (EBV)
Human herpesvirus 6 (HHV6)
Parvovirus B19 (B19V)
Mumps virus (MV)
Human Parechovirus (HPeV)
Human Adenovirus (AdV)
Human Enterovirus (HEV)
Haemophilus influenzae (HI)
Streptococcus pneumoniae (SP)
Listeria monocytogenes (LM)
Neisseria meningitidis (NM)
Streptococcus agalactiae (GBS)
Escherichia coli K1 (EC K1)
Cerebrospinal fluid (CSF)
Cerebrospinal fluid (CSF) should be aseptically collected in a sterile container by the physician using aspiration techniques.
Auto Extraction & PCR Setup
Seegene NIMBUS
Seegene STARlet
Real-time PCR
CFX96 Touch™ Real-Time PCR Detection System (Bio-Rad)
CFX96™ Dx System (Bio-Rad)
CFX96™ Opus (Bio-Rad)
CFX96 Touch™ Real-Time PCR Detection System (Bio-Rad)
Seegene Viewer
- Quick and easy data analysis and interpretation
- Interface specialized for multiplex testing
- Simultaneous detection and identification of 18 pathogens causing meningitis in three tubes
- Multiplex real-time RT- PCR assay in <4 hours (including extraction and PCR)
- Provides individual cycle threshold (Ct) value of multiple targets in a single reaction
- Large panel coverage of target pathogens
- High throughput testing on automated platform
Select the assays you are interested in and a Seegene representative will contact you to complete your order.
1 Confederation Of Meningitis Organisations Inc. 2 Centers for Disease Control and Prevention