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Novaplex™ Entero-DR Assay
Simultaneous detection and identification of 8 antibiotic resistance genes

Hospital Acquired Infection

2.8
million

In the U.S., more than 2.8 million antimicrobial-resistant infections occur each year.

35,000

More than 35,000 people die as a result, according to CDC’s 2019 Antibiotic Resistance (AR) Threats Report.1

Understanding Hospital Acquired Infection

Drug Resistance impacts human healthcare but also veterinary, and agriculture industries. Antibiotic resistant bacteria have become a global concern in clinical and public health aspects due to their ability to resist the effects of antibiotics. Antibiotic resistant bacteria spread from person to person in the community (community-acquisition) or from patient to patient in hospital (hospital acquisition). Three major bacteria that acquired antibiotic resistance include carbapenemase-producing Enterobacteriaceae (CPE), vancomycin-resistant Enterococci (VRE), and extended-spectrum beta-lactamases-producing Enterobacteriaceae (ESBL). 


Novaplex™ Entero-DR Assay* is a multiplex Real-time PCR assay that detects and identifies 8 antibiotic resistance genes simultaneously. Based on Seegene’s proprietary MuDT™ technology, this assay reports multiple Ct values of each target in a single channel without melting curve analysis.

*Novaplex™ Assays are For Research Use Only. Not for Use in Diagnostic Procedures.

Product Information
Analytes

Carbapenemase genes (NDM)
Carbapenemase genes (KPC)
Carbapenemase genes (OXA48)
Carbapenemase genes (VIM)
Extended Spectrum Beta Lactamase (ESBL)
Carbapenemase genes (IMP)
CTX-M
Vancomycin resistance genes (VanA, VanB)

Specimen

Rectal swab
Bacterial colony

Compatible instrumentation

Automated Extraction & PCR Setup
Seegene NIMBUS
Seegene STARlet

Real-time PCR
CFX96™ Real time PCR Detection System (Bio Rad)
CFX96™ Opus (Bio-Rad)
CFX96 Touch™ Real Time PCR Detection System (Bio Rad)

Seegene Viewer Software

  • Quick and easy data analysis and interpretation
  • Interface specialized for multiplex testing
Key Features
  • Detection of 3 major antibiotic resistant bacteria in a single reaction 
    • Differentiation of each resistance gene 
  • Provides whole process control for assay validity 
  • Reports individual Ct values increases productivity for detection of all 8 targets in a single reaction 
  • Multiplex test provides 768 data points (8 targets/test) for 96 samples within 4 hours for rectal swab.
Ordering Information

Select the assays you are interested in and a Seegene representative will contact you to complete your order.

Step 1 of 2

Product
1 2019 Antibiotic Resistance Threats Report. Centers for Disease Control and Prevention. (2021). Retrieved from https://www.cdc.gov/drugresistance/biggest-threats.html
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