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Novaplex™ Entero-DR Assay
Simultaneous detection and identification of 8 antibiotic resistance genes

Hospital Acquired Infection

2.8
million

In the U.S., more than 2.8 million antimicrobial-resistant infections occur each year.

35,000

More than 35,000 people die as a result, according to CDC’s 2019 Antibiotic Resistance (AR) Threats Report.1

Product Information
  • Analytes
    • Carbapenemase genes (NDM)
    • Carbapenemase genes (KPC)
    • Carbapenemase genes (OXA48)
    • Carbapenemase genes (VIM)
    • Extended Spectrum Beta Lactamase (ESBL)
    • Carbapenemase genes (IMP)
    • CTX-M
    • Vancomycin resistance genes (VanA, VanB)
    This product has multiple variants. The options may be chosen on the product page
Specimen

Rectal swab
Bacterial colony

Compatible instrumentation

Automated Extraction & PCR Setup
Seegene NIMBUS
Seegene STARlet

Real-time PCR
CFX96™ Real time PCR Detection System (Bio Rad)
CFX96™ Opus (Bio-Rad)
CFX96 Touch™ Real Time PCR Detection System (Bio Rad)

Seegene Viewer Software

  • Quick and easy data analysis and interpretation
  • Interface specialized for multiplex testing
Key Features
  • Detection of 3 major antibiotic resistant bacteria in a single reaction 
    • Differentiation of each resistance gene 
  • Provides whole process control for assay validity 
  • Reports individual Ct values increases productivity for detection of all 8 targets in a single reaction 
  • Multiplex test provides 768 data points (8 targets/test) for 96 samples within 4 hours for rectal swab.
Understanding Hospital Acquired Infection

Drug Resistance impacts human healthcare but also veterinary, and agriculture industries. Antibiotic resistant bacteria have become a global concern in clinical and public health aspects due to their ability to resist the effects of antibiotics. Antibiotic resistant bacteria spread from person to person in the community (community-acquisition) or from patient to patient in hospital (hospital acquisition). Three major bacteria that acquired antibiotic resistance include carbapenemase-producing Enterobacteriaceae (CPE), vancomycin-resistant Enterococci (VRE), and extended-spectrum beta-lactamases-producing Enterobacteriaceae (ESBL). 


Novaplex™ Entero-DR Assay* is a multiplex Real-time PCR assay that detects and identifies 8 antibiotic resistance genes simultaneously. Based on Seegene’s proprietary MuDT™ technology, this assay reports multiple Ct values of each target in a single channel without melting curve analysis.

*Novaplex™ Assays are For Research Use Only. Not for Use in Diagnostic Procedures.

1 2019 Antibiotic Resistance Threats Report. Centers for Disease Control and Prevention. (2021). Retrieved from https://www.cdc.gov/drugresistance/biggest-threats.html
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