Multidrug-Resistant Mycobacterium tuberculosis
For the simultaneous detection of 13 mutations associated with resistance to MTB, rpoB, katG and inhA promoter.
Product Information

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  • Novaplex™ MTB/MDR Detection

    Novaplex™ MTB/MDR Detection
    Targets
    • Mycobacterium tuberculosis (MTB)
    • RIF-R (18 mutations in rpoB)
    • INH-R (4 mutations in katG)
    • INH-R (3 mutations in inhA promoter)
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    This product has multiple variants. The options may be chosen on the product page
  • Novaplex™ MTB/MDRe Detection

    Novaplex™ MTB/MDRe Detection
    Targets
    • Mycobacterium tuberculosis (MTB)
    • RIF-R (18 mutations in rpoB)
    • INH-R (4 mutations in katG)
    • INH-R (3 mutations in inhA promoter)
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    This product has multiple variants. The options may be chosen on the product page
  • Novaplex™ MTB/XDRe Detection

    Novaplex™ MTB/XDRe Detection
    Targets
    • Mycobacterium tuberculosis (MTB)
    • Extensive drug resistance (13 mutations)
    • Injectable drug-resistance (6 mutations)
    • Fluoroquinolone-resistance (7 mutations)
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    This product has multiple variants. The options may be chosen on the product page
Sample Types
  • Sputum
  • Cultured cells
  • Fresh tissue in the same sample types
  • Bronchial wash
Compatible instrumentation

Auto Extraction & PCR Setup

  • Seegene NIMBUS
  • Seegene STARlet

Real-time PCR

  • CFX96™ Real-time PCR Detection System (Bio-Rad)
  • CFX96™ Dx (Bio-Rad)
  • CFX96™ Touch (Bio-Rad)
  • CFX96™ Opus (Bio-Rad)

Seegene Viewer Software

  • Quick and easy data analysis and interpretation
  • Interface specialized for multiplex testing
Key Features
  • Simultaneous detection of Mycobacterium tuberculosis and over 30 genes associated with resistance causing mutations
  • Ct value and qualitative drug-resistance result in a single test
Multidrug-Resistant Tuberculosis information

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The Novaplex™ II MTB/MDR* multiplex real-time PCR assay simultaneously detects Mycobacterium tuberculosis (MTB) and genes associated with resistance causing mutations.

The Novaplex™ II MTB/XDR* PCR assay simultaneously detects Mycobacterium tuberculosis (MTB) and genes associated with resistance causing mutations gyrA A90V(GTG), S91P(CCG), D94A(GCC), D94H(CAC). D94Y(TAC), rrs 1401(G), 1402(T), eis promoter -37(T), -14(T), -10(A)], and internal Control (IC).

The Novaplex™ MTB/MDRe Detection* multiplex real-time PCR system for detection of Mycobacterium tuberculosis and genes associated with resistance causing mutations katG S315I(ATC), S315N(AAC), S315T(ACC), S315T(ACA), inhA promoter -15(T), -8(A), -8(C)], 18 rpoB L511P(CCG), Q513K(AAA), Q513L(CTA), Q513P(CCA), 3 amino acid-deletion in 513~516, D516V(GTC), D516Y(TAC), S522L(TTG), S522Q(CAG), H526C(TGC), H526D(GAC), H526L(CTC), H526N(AAC), H526R(CGC), H526Y(TAC), S531L(TTG), S531W(TGG), L533P(CCG)], and Internal Control (IC).

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  • Novaplex™ Assays are For Research Use Only. Not for Use in Diagnostic Procedures.
  • Seegene NIMBUS, Seegene STARlet, Seegene Launcher and Viewer software are For Research Use Only. Not for Use in Diagnostic Procedures.
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